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May 13, 2024
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CHEM 435 Introduction to ImmunologyCredit 3
Introduction to Immunology is designed to present a complete overview of the process regulating the immune response. Lecture will first provide an overview of the immune system organization, cellular and organ components, and general function. The evolution of the immune system is emphasized through the major scientific discoveries that have contributed to the current understanding of the immune system. Mechanisms of innate immunity will be introduced followed by discussion of antibodies and antibody diversity, antigens, and antigen-antibody interactions. Adaptive immunity will also be discussed: major histocompatibility complex function, B and T cell development and differentiation, antigen recognition by B and T cell receptors, generation of lymphocyte antigen receptors, antigen presentation to T lymphocytes, and the development and survival of lymphocytes. Lectures will transition to an introduction to cytokines and their role in regulation of immune responses and the role of the complement system and cell-mediated effector response. Lastly, this course will explore the roles of the immune system in disease prevention with a focus on adaptive immunity to infection, vaccination, and cancer immunology. Consequences of abnormal immune responses such as mechanisms for rejection of transplanted tissue and autoimmunity will also be reviewed. Prerequisite(s): BIOL 326 /BIOL 327 , CHEM 341 /CHEM 343 , CHEM 342 /CHEM 344 .
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